Can horizontal websites work for the lodging industry ?

The novelty of a horizontal scrolling website can make your brand more memorable and share-able online, but is it practical for all industries ?

Web Design Ledger compiled a list of 25 beautiful and creative horizontal websites here:

There's no doubt that these websites grab your attention and make you want to explore every nook and cranny. This is great from the standpoint of engaging your visitors, but you'll notice that many of these websites are purely informational. Very few of these websites feature traditional e-commerce shopping carts or booking engines. 

But what do you think ? Is it because users are so accustomed to a particular format when making purchases online, that they will be uncomfortable using a new scheme ? Do you see horizontal website compositions becoming popular for the lodging industry ?